The upregulation of IL10 production may be involved in the prolonged clinical benefit
Rheumatoid arthritis (RA) is a common inflammatory disease characterized by progressive bone and cartilage destruction that results in severe functional limitations
The upregulation of IL10 production may be involved in the prolonged clinical benefit
In a private clinic there were 187 patients from mines and
We developed a novel pH-sensitive drug delivery system of dexamethasone (Dex) based on an N - (2-hydroxypropyl)methacrylamide copolymer (P-Dex) and have
Abatacept eases symptoms and prevents joint damage in rheumatoid arthritis patients by dampening the immune system, researchers said
Brand names: Dexamethasone Intensol, Zcort, TaperDex, Hemady, ZoDex HiDex Dxevo De-Sone LA Dexabliss
Results from a Phase 2b clinical trial
MONDAY, April 17, 2023 (HealthDay News) -- Arthritis is a common disease that causes pain and inflammation in different body joints, making it difficult to enjoy everyday tasks
However, the clinical application is limited by their nonspecific distribution after systemic administration, serious adverse reactions during long-term administration
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease associated with persistent synovitis, joint and cartilage damage, and osteoporosis (1,2,3)
Incorporation with thioether lipids and a FA segment significantly improved the triggered
Among interventions for RA, rituximab is considered a biologic disease-modifying antirheumatic
A novel linear multifunctional polyethylene glycol (PEG)-dexamethasone (Dex) conjugate (click PEG-Dex) was synthesized using facile Cu (I)-catalyzed Huisgen 1,3-dipolar cycloaddition (a click reaction)
The effect of DXP-NPs on paw arthritis inflammation score and volume of hind paw edemas was compared to free dexamethasone sodium phosphate (DSP) and PBS as negative control (Fig
Thirty rheumatoid
Methotrexate is usually the first medicine given for rheumatoid arthritis, often with another DMARD and a short course of steroids (corticosteroids) to relieve any pain
High-capacity loading and a sustained release of target drugs were achieved by radially oriented mesopores and
while dexamethasone treatment can promote the survival of M2 type Radially mesoporous silica nanoparticles (RMSNs) with protonated amine functionality are proposed to be a dexamethasone (Dex) carrier that could achieve a sustained anti-inflammatory effect in rheumatoid arthritis (RA)
Administration for prolonged periods or repeatedly during