Ondansetron has widespread utility as an antiemetic drug and is effective against nausea and vomiting of various etiologies
Uses
This medication treats vomiting, nausea, and
Ondansetron is a specific 5HT 3 -receptor antagonist which blocks 5HT 3 receptors in the gastro-intestinal
Five neurotransmitter receptor sites are of primary
Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur
This drug is used to relieve symptoms of nausea and vomiting caused by various factors such as chemotherapy, radiation therapy, as well as surgery
Patients with a history of hyperemesis gravidarum may need higher doses of antiemetic prophylaxis (eg, ondansetron 8 mg every 8 hours scheduled for 24 hours or metoclopramide 10 mg every 8 hours, then as needed to prevent nausea/vomiting)
You usually have it with other Safety and tolerability
But some antiemetic drugs work better in certain instances than others
Chemotherapy often causes nausea and vomiting
These actions result in reducing symptoms of nausea and vomiting in affected patients
Common uses of ondansetron include the prevention of chemotherapy-induced and radiation-induced nausea and Ondansetron is an antiemetic medication prescribed to prevent nausea and vomiting caused by cancer treatments (chemotherapy and radiation, and anesthetic medications used during surgeries)
Once administered, it acts as a neurokinin receptor antagonist that blocks Ondansetron is the only intervention that revealed an effect on the cessation of vomiting, on preventing hospitalizations, and in reducing the need for intravenous rehydration
How this is relevant to clinical practice Aromatherapy was a more potent antiemetic than oral ondansetron in this sample of nauseated emergency department adults without intravenous access
Ondansetron has shown good efficacy in the prevention of acute nausea and vomiting in children receiving moderately or highly emetogenic chemotherapy and/or irradiation, particularly when combined with dexamethasone
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5-2 hours prior to chemotherapy
Subacute intestinal obstruction — ondansetron increases large bowel transit time
Anticholinergic antiemetics are mainly used to prevent or treat motion sickness