Each film-coated tablet contains ribociclib succinate, equivalent to 200 mg ribociclib
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The main result of the study, or primary end point, was PFS
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It works by blocking oestrogen getting into the breast cancer cell
Ribociclib plus endocrine therapy (ET) demonstrated a statistically significant progression-free survival and overall survival 3
Otherwise, it is not subsidised and people have to pay the full price for it themselves
In the three pivotal studies and Study X2107, the recommended dose modification scheme to manage study drug-related AEs is to reduce the dose from 600 mg to 400 or 200 mg
The estimated overall survival at 42 months was 57